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Keyword - RNA suppression of termination (KW-1159)

Definition

Protein which is derived from an mRNA by suppression of termination, a process in which a tRNA misreads a termination codon thereby producing a longer protein. RNA secondary structure after the stop codon plays a role in this process. The efficiency of suppression of termination is about 10% for most viruses. Termination suppression is involved in polyprotein synthesis of gamma and epsilon retroviruses, as well as all togaviridae.

Category

Coding sequence diversity

Graphical

RNA suppression of terminationCoding sequence diversity
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